Terraria Brain of Cthulhu Boss Guide

If you thought The Eye of Cthulhu was terrifying, wait until you see its brain! 

Today we’ll show you how to take down this eldritch fiend once and for all!

Terraria Brain of Cthulhu Boss Phase 1

The Brain of Cthulhu pre-fight preparations

  • Splash damage and piercing styled weapons to help with smaller enemies.
  • Plenty of room in your arena to move around in
  • A large number of spiky balls 
  • Potions to counter the various debuffs the brain can afflict you with on expert mode and above.

What the boss, Brain of Cthulhu can do

The Brain of Cthulhu itself is capable of summoning smaller entities known as creepers to attack and harass the player. While they don’t have much health, they can quickly swarm the player in their odd patterns. The player’s position relative to the brain is what determines the movement of the swarm. 

The brain is also capable of teleporting sporadically throughout the battle. When this happens, be sure to watch for the creepers as they move between the player and the brain in an orbital pattern. The brain is also capable of ramming into the player at a reasonably high speed. 

In combination with teleporting, this ram can make this monster wildly unpredictable. In expert mode, the brain is capable of inflicting the following ailments: poisoned, darkness, cursed, bleeding, confused, slow, silenced, weak, broken armor. 

Your options

You will need to bring something such as a grenade to take down the multitude of creepers. You can also pack other explosives or even spiky balls to lure the creepers into either above or below you. 

While you can melee them on easier difficulties, this becomes significantly more dangerous on more challenging modes due to the debuff chance. Given that you’ll have a crimson biome, you can opt to craft a crimson rod and stay underneath its attack as it functions as area denial. 

An aqua scepter can make short work of the creepers and hit multiple at the same time.

The Brain of Cthulhu strategy

You’ll want an arena with several rows for this battle. Litter the floor with spiky balls before starting the fight. As the fight begins, run toward the arena and wait for the brain to summon the creepers. 

You cannot hurt the brain during this phase, so shift your focus on either meleeing the eyes or hitting them with a grenade. Once you’ve taken care of the eyes, the brain will become vulnerable. 

Terraria Brain of Cthulhu Boss Phase 2

Be wary of its teleport, and be sure to dodge it while luring it into the spiky balls. If the brain lunges at you, opt to either jump a row higher or fall a floor lower. If you have any powerful single-target attacks such as a fire of flower or a shotgun, now is your time to use them against the brain. 

While it’s moving toward you, try to take aim and fire preemptively. 

Keep whittling it down while getting in hits when you can, and you can eradicate this eldritch horror!

No brain, no pain

Now that you’ve successfully taken down one of the main threats of the crimson biome, you’ll be able to reap your rewards. The Terraria boss fights don’t end there though, be sure to check out the rest of our guides!

If you really get stuck trying to take down the Brain of Cthulhu, there’s plenty of video guides out there to assist you.

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About Digital Ghost

Dg is the founder and co-owner of Corrosion Hour, a niche gaming community established in 2016 focusing on the survival game RUST. He is an active and contributing member of numerous other RUST communities. As a community leader and server owner for over 15 years, he spends much of his time researching and writing guides about survival games, covering topics such as server administration, game mechanics, and community growth.

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